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Having a therapy that has been shown to address multiple symptoms of Rett syndrome provides a promising treatment option that may lead to meaningful impact for patients and their families. A calibrated measuring device (eg, oral syringe, oral dosing cup) should be obtained from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study (ClinicalTrials. The dosage is determined by patient weight and can be administered orally or via gastrostomy tube. Findings showed that treatment with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints). The product, which received FDA approval in March 2023, was approved based on data from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study farxiga and januvia (ClinicalTrials.

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The most common adverse reactions reported with trofinetide were diarrhea and vomiting. A calibrated measuring device (eg, oral syringe, oral dosing cup) should be obtained from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study (ClinicalTrials. The dosage is determined by patient weight and can be administered farxiga and januvia orally or via gastrostomy tube. Daybue is supplied as a strawberry-flavored oral solution containing 200 mg of trofinetide per mL. The dosage is determined by patient weight and can be administered orally or via gastrostomy tube.

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What may interact with Januvia?

Using certain medicines can make it harder for you to tell when you have low blood sugar. Tell your doctor if you use albuterol, clonidine, reserpine, or a beta-blocker (atenolol, metoprolol, propranolol, and others).

Before you take Sitagliptin, tell your doctor if you are also taking digoxin (Lanoxicaps, Lanoxin).

Although Sitagliptin is not as likely to cause hypoglycemia (low blood sugar) as some other oral diabetes medications, tell your doctor if you are taking any other drugs that can potentially lower blood sugar, such as:

• probenecid (Benemid);
• nonsteroidal anti-inflammatory drugs (NSAIDs);
• aspirin or other salicylates (including Pepto-Bismol);
• a blood thinner (warfarin, Coumadin);
• sulfa drugs (Bactrim, SMX-TMP, and others);
• a monoamine oxidase inhibitor (MAOI); or
• beta-blockers (Tenormin and others).
• insulin or other oral diabetes medications.

This list is not complete. Other drugs may interact with Sitagliptin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

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